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1 month ago

Vice President, Clinical Development – Cardiovascular

Ionis Pharmaceuticals - Carlsbad, CA 92010

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career! VICE PRESIDENT, CLINICAL DEVELOPMENT - CARDIOVASCULAR SUMMARY: The Vice President, Clinical Development – Cardiovascular is responsible for defining and driving the clinical development strategy for Ionis’ cardiovascular portfolio and for contributing to enterprise-level development and portfolio decisions. This role operates with a high degree of independence and accountability, directly influencing corporate strategy, portfolio prioritization, and investment decisions. The VP partners closely with senior leadership across Development, Research, Regulatory Affairs, and Commercial to ensure that clinical programs are scientifically rigorous, operationally executable, and positioned to deliver meaningful value to patients and the company. The VP is accountable for advancing multiple clinical programs across stages of development, including phase 4 and post marketing studies, and for making complex, high-impact decisions in areas where data may be limited and risk is significant. This role will report to the Senior Vice President, Global Cardiovascular Development and will manage direct reports. RESPONSIBILITIES: Maintain deep expertise in cardiovascular and cardiometabolic disease, including lipid disorders such as hypercholesterolemia, hypertriglyceridemia, and lipoprotein(a)–mediated risk. Apply current and emerging science in lipid biology and cardiovascular risk reduction to inform clinical development strategies and portfolio decisions. Guide development of clinical programs targeting lipid-modifying therapies, including selection of appropriate patient populations, biomarkers, and endpoints. Provide leadership on the design and interpretation of cardiovascular outcomes trials (CVOTs) and other studies evaluating impact on major adverse cardiovascular events (MACE). Integrate translational insights (e.g., mechanism of action, biomarker response, genetic validation) into clinical development plans to strengthen probability of success. Guide interpretation of complex clinical and biomarker data, including lipid parameters and cardiovascular risk markers, and translate findings into strategic program decisions. REQUIREMENTS: M.D. with significant experience in clinical development within the biopharmaceutical industry. Deep expertise in cardiovascular disease, with strong experience in lipid disorders and cardiometabolic disease (e.g., dyslipidemia, atherosclerosis, triglyceride metabolism, Lp(a)). Demonstrated success leading development of therapies targeting cardiovascular risk factors, including experience with lipid-modifying agents and/or outcomes-based clinical programs. Experience designing and interpreting studies involving lipid biomarkers, surrogate endpoints, and cardiovascular outcomes (e.g., MACE). Proven ability to translate mechanistic and translational science (including genetics and biomarker data) into clinical development strategy. Demonstrated success leading clinical development programs across multiple stages, including late-stage development. Proven ability to make high-quality decisions in complex, ambiguous situations with meaningful business impact. Experience influencing portfolio strategy and contributing to investment or prioritization decisions. Strong leadership and influencing skills, with the ability to drive outcomes across cross-functional teams. Experience interacting with regulatory agencies and external experts. Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position; reference requisition #IONIS003999 Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits Full Benefits Link: https://ionis.com/careers#:~:text=Highly%20competitive%20benefits The pay scale for this position is $338,814 to $423,694 NO PHONE CALLS PLEASE. PRINCIPALS ONLY. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

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1 month ago

Receptionist Bilingual Spanish

The GEO Group, Inc. - Escondido, CA

Benefits Information: Benefits: As an Administrative Assistant, you will be part of a stable, established, and yet still growing organization with a great deal of diversification, which will present you with a range of different challenges. Since we do prefer to promote from within, you will have opportunities to move to other facilities as well as to different divisions within the company. We value your hard work and professional dedication and will reward you with a competitive compensation package that includes full benefits. Two (2) weeks of Vacation Fifty-six (56) Hours of sick time Fifteen (15) paid Holidays Medical, Dental, and Vision coverage Term and Whole life insurance (includes spouse and dependent) Accidental death and dismemberment insurance Short- and long-term disability Flexible spending account 401(k) retirement program Stock purchase program Tuition reimbursement - $3500 per year Employee Assistance Program (EAP) Legal program – Legal Club of America Direct deposit Theme Park and attraction discounts The compensation and benefits information are accurate as of the date of this posting. The Company reserves the right to modify this information at any time, with or without notice, subject to applicable law. Equal Opportunity Employer Overview: Since inception in 2004, BI Incorporated has operated ISAP for the Department of Homeland Security (DHS) and U.S. Immigration and Customs Enforcement (ICE) and Enforcement and Removal Operations (ERO). ISAP is an essential part of ERO, providing intensive supervision of individuals in immigration proceedings. The program achieves positive results by combining comprehensive case management with proven supervision technology. In addition, BI maintains an extensive list of community-based partners to provide critical assistance for participants' basic life needs. With consistent positive outcomes, ISAP continues to grow and evolve, serving an ever-increasing number of participants. Qualifications: Minimum Requirements: High School Diploma or GED. At least two (2) years of work experience in a similar position, including experience working with multi-cultural contacts preferred. Ability to pass a federal background check and obtain a suitability determination. United States citizenship required. Must live in the United States three (3) of the last five (5) years (military and study abroad accepted). Bilingual Spanish required. Good computer skills. Effective communication skills with internal and external contacts. Good interpersonal skills. Ability to deal tactfully with the public. Sound judgment and even temperament. Ability to maintain self-control in stressful situations, such as interpersonal confrontations or emergencies. Ability to deal with multi-cultural contacts with sensitivity. Good organizational skills. Attention to detail. Working knowledge of Microsoft Word, Excel and Outlook. Ability to work with computers and the necessary software typically used by the department. Working Conditions: Encountered on a regular basis as part of the work this job performs. Typical office environment. Some local travel may be required. Use of standard office equipment such as copier, computer, keyboard, telephone and fax machine. Ability to use hands and fingers to perform data entry. Responsibilities: Summary: Provides administrative and clerical support for an Intensive Supervision Appearance Program (ISAP) office. Primary Duties and Responsibilities: Greets and communicates with ISAP program participants, community visitors, agency personnel and general visitors. Ensures that program participants are properly checked in for office visits. Answers the phones and directs calls appropriately. Maintains program participant case records on the computer system by performing data entry. Maintains files and other related documentation. Assists the Program Manager and Case Specialists with case coordination, communication with the contracting agency and routine clerical tasks. Coordinates transportation services for program participants. Performs other duties as assigned. Pay: Pay USD $20.00/Hr.

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1 month ago

Director of Finance

Casino Pauma - Pauma Valley, CA 92061

SUMMARY: Responsible for taking on a leadership role in financial decision-making that affects Casino Pauma, including future development and expansion. Will provide strategic, financial and operational recommendations to the General Manager and the Enterprise Board. While Overseeing Accounting, Finance, Information Technology, Cage/Count Room Operations and Purchasing, the CFO will play a key role in developing and implementing both financial and operational procedures to improve and maintain the financial success of the company. ESSENTIAL DUTIES & RESPONSIBILITIES: Directs and provides leadership for Cage/Count Operations, IT, Purchasing, Accounting and Revenue Audit. Ensures credibility of Finance by providing timely and accurate analysis of financial trends and forecasts. Develops, analyzes and interprets statistical and accounting information in order to assess operating results. Monitors and measures profitability and performance against budget, prior year and industry benchmarks. Establishes major economic objectives and policies for Casino Pauma and prepares reports that detail the company's financial position in the areas of income, expenses, and earnings. Analysis and development of policies, procedures and systems to ensure effective internal controls, optimum efficiencies and improvement of processes. Provides the leadership team with information in order to improve Service, Revenue, and Profit. Coordinates all audit and banking relationships and provides required reports. Participates insurance reviews: Health and Liability in order to assess risks and minimize losses. Furnishes and presents internal reports as requested on financial and operational effectiveness. Ensures that financial records are maintained in accordance with GAAP and GASB. Ensures and enforces compliance with NIGC and Tribal minimum internal controls, and State Compact. Understands and ensures compliance with all of the property's contractual documents. Strong interpersonal skills, ability to communicate and manage well at all levels of the organization. Excellent problem solving and creative skills. Ability to exercise sound judgment and make decisions based on accurate and timely analyses. High level of integrity and dependability with a strong sense of urgency and results-orientation. Assist in the preparation, negotiation, implementation, and monitoring on a timely basis, contracts and agreements that will enable the Casino to achieve its goals and objectives. Provide reports/recommendations to strategically enhance financial performance and business opportunities. Special projects as requested by the General Manager or the Enterprise Board. MINIMUM QUALIFICATIONS: 10 - 15 years financial / accounting industry experience with a minimum of 10 years in a casino environment. Prior experience as a VP of Finance at a casino (required). Pre-opening/expansion experience preferred. Previous experience with all of the following Casino and related Systems: Slots, Tables Games, Soft Count, Financial Accounting, Revenue Audit, Point of Sale, Hotel, and other hospitality related systems etc. Operations experience in Cage/Count, Accounting/Auditing, Information Technology, and Purchasing. Solid experience building and managing teams of people. Proven track record in providing leadership in accounting, compliance, budgeting, operational/financial analysis and business process improvement. Excellent analytical skills. Current and relevant gaming industry knowledge. Proficient with GAAP and GASB. Must have excellent knowledge of the NIGC MICS. Excellent organization and communication skills, both written and verbal. Must be proficient in Microsoft Windows, Word, and Excel. EDUCATION: High School Diploma or GED (required). Bachelor’s Degree (required), preferably Business Administration, Finance or Accounting. Master’s Degree / CPA/ CMA designation (desirable). PHYSICAL / MENTAL REQUIREMENTS (Constantly, Frequently, Occasionally): Constantly sitting, walking and standing. Constant hearing, seeing and talking. Frequently balancing, bending, reaching, twisting, holding, wrist motion, and stooping. WORKING CONDITIONS: Work is performed indoors in a climate-controlled environment. Close spaces while working with others. Moderate noise levels. LICENSE REQUIREMENTS: Must be able to successfully pass a pre-employment drug screen, background investigation, and maintain a Pauma Gaming Commission License. NATIVE AMERICAN PREFERENCE STATEMENT Pauma Band of Mission Indians, a federally recognized Indian Tribe, in accordance with section 703(i) of Title VII of the Civil Rights Act of 1964, will give preference to Native Americans who meet job position minimum qualifications with regard to hiring, promotions, transfers and training.

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1 month ago

Crew

Chipotle Mexican Grill - Escondido, CA 92025

CULTIVATE A BETTER WORLD Food served fast does not have to be a typical fast-food experience. Chipotle has always done things differently, both in and out of our restaurants. We are changing the face of fast food, starting conversations, and directly supporting efforts to shift the future of farming and food. We hope you will join us as we continue to learn, evolve, and shape what comes next on our mission to make better food accessible to everyone. THE OPPORTUNITY At Chipotle, we’ve created a better place to eat and work. Many employees start just expecting a paycheck but end up with a rewarding career. We provide exceptional training and a clear career path – over 80% of our managers were promoted from Crew. We prepare real food by hand every day in our restaurants. No freezers, microwaves or can openers to be found. We’ll provide the training you need to feel confident working at any station – grill, cashier, prep, salsa and expo. We take pride in our exceptional customer service and it’s up to each of our team members to create the friendly atmosphere that our customers expect and enjoy. So, whether you have experience as a dishwasher, cashier, server, host, bartender, cook, prep cook or no experience at all, we’re always looking for passionate and enthusiastic people to join our team. If this sounds like something you’d like to be a part of, we’d love to meet you! See more details below and apply today. WHAT’S IN IT FOR YOU Tuition assistance (100% coverage for select degrees or up to $5,250/year) Free food (yes, really FREE) Medical, dental, and vision insurance Digital Tips Paid time off Holiday closures Competitive compensation Full and part-time opportunities Opportunities for advancement (80% of managers started as Crew) WHAT YOU’LL BRING TO THE TABLE A friendly, enthusiastic attitude Passion for helping and serving others (both customers and team members) Desire to learn how to cook (a lot) Be at least 16 years old Ability to communicate in the primary language(s) of the work location PAY TRANSPARENCY Below is the base pay range for this position, which is also eligible for digital tips. Actual base pay may vary depending on skill level, experience and/or education. In addition to base pay, Chipotle offers a competitive benefits package. Visit https://jobs.chipotle.com/benefits for more details. $20.00–21.00 WHO WE ARE Chipotle Mexican Grill, Inc. (NYSE: CMG) is cultivating a better world by serving responsibly sourced, classically cooked, real food with wholesome ingredients without artificial colors, flavors or preservatives. Chipotle has restaurants in the United States, Canada, the United Kingdom, France and Germany and is the only restaurant company of its size that owns and operates all its restaurants in North America and Europe. With employees passionate about providing a great guest experience, Chipotle is a longtime leader and innovator in the food industry. Chipotle is committed to making its food more accessible to everyone while continuing to be a brand with a demonstrated purpose as it leads the way in digital, technology and sustainable business practices. For more information or to place an order online, visit www.chipotle.com. Chipotle Mexican Grill is an equal opportunity employer that values diversity at all levels. As a people-first company rooted in values, our purpose extends beyond serving nutritious food using real ingredients. It means hiring world-class individuals and fostering a culture that champions diversity, ensures equity, and celebrates inclusion. All qualified applicants, regardless of personal characteristics, are encouraged to apply. Qualified applicants with disabilities may be entitled to reasonable accommodation under the terms of the Americans with Disabilities Act and/or certain state or local laws. Please contact [email protected] if you need an accommodation due to a disability to complete an application, job interview, and/or to otherwise participate in the hiring process. This email does not respond to non-accommodations related requests.

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1 month ago

Electrical Instrumentation Technician – I, II

City of San Clemente, CA - San Clemente, CA

Description The City of San Clemente invites applications for: Electrical Instrumentation Technician I, II Electrical Instrumentation Technician I: $45.66-$55.50 Electrical Instrumentation Technician II: $50.34-$61.19 The City of San Clemente is seeking skilled and motivated candidates to join our Utilities Division as Electrical Instrumentation Technicians. This is a unique opportunity to work on critical infrastructure supporting the City's water and wastewater systems, including electrical controls, instrumentation, and data communication systems. This position offers hands-on, technical work with opportunities to troubleshoot, repair, and maintain complex electrical and electronic systems that directly support essential public services. The classification is flexibly staffed, providing a clear path for career growth from trainee to journey-level technician based on performance and certification. If you are looking to build or expand your career in the electrical/instrumentation field while contributing to essential City operations, we encourage you to apply! DEFINITION To perform a variety of routine, semi-skilled, skilled, and highly skilled assignments in the maintenance, repair and installation of electrical equipment including water and sewer systems, data radio systems, and electronic monitoring systems; to overhaul, construct and salvage electrical machinery and equipment; and to perform a variety of tasks relative to assigned area of responsibility. DISTINGUISHING CHARACTERISTICS Work assignments are allocated in recognition of the scope and difficulty of the work assignments, and the certification levels of employees: Electrical Instrumentation Technician I - This is the entry-level class in the Electrical Instrumentation Technician series reflecting work performed under closer supervision and procedural controls. Positions at this level have prior experience but are not expected to function with the same amount of program knowledge or skill level as positions allocated to the Electrical Instrumentation Technician II level and exercise less independent discretion and judgment in matters related to work procedures and methods. Work is usually supervised while in progress and fits in an established structure or pattern. Electrical Instrumentation Technician II - This is the full journey level class in the Electrical Instrumentation Technician series reflecting the full range of semi-skilled and journey-level duties with only occasional instruction or assistance. Positions at this level are distinguished from the Electrical Instrumentation Technician I level by the performance of the full range of duties as assigned, working independently, and exercising judgment and initiative. Positions at this level receive only occasional instruction or assistance as new or unusual situations arise, and are fully aware of the operating procedures and policies of the work unit. Work is normally reviewed at critical points of assigned project for soundness of technical judgment and to determine if desired overall objectives have been achieved. Positions in this class series are flexibly staffed and positions at the Electrical Instrumentation Technician II level are normally filled by advancement from the Electrical Instrumentation Technician I level. Advancement to the “II” level is based on demonstrated proficiency in performing the assigned functions, appropriate certification, and the discretion of supervisory or management staff. Essential Functions ESSENTIAL FUNCTION STATEMENTS - Class specifications are intended to present a descriptive list of the range of duties performed by employees in the class. Specifications are not intended to reflect all duties performed within the job. Essential and other important responsibilities and duties may include, but are not limited to, the following: Electrical Instrumentation Technician I/II Perform a variety of functions in the repair, maintenance, installation and construction of electrical machinery, equipment and systems, including water and sewer systems and data radio systems. Plan, prioritize and participate in the more complex electrical projects, including overhauling construction and salvaging electrical machinery and equipment. Install underground cable and other electrical devices; install conduits in buildings and underground; install service entrance equipment for all voltages and phases. Install reservoir level controls; calibrate reservoir levels. Repair and maintain data radio communication systems, including booster stations; install systems and set up computer base; troubleshoot system problems. Read and interpret blueprints and schematic drawings; locate, identify and mark underground utilities; locate and upgrade code infractions. Operate a bucket truck, pneumatic tools, trenchers, diggers, compressors and small power tools. Estimate time, materials and equipment required to complete assigned jobs; requisition materials as required. Respond to after hour electrical emergencies. A 45-minute response time is required. Perform related duties and responsibilities as required. Typical Qualifications Knowledge of: Principles and practices of electrical construction. Techniques and procedures of skilled maintenance. Occupational hazards and standard safety practices necessary in the area of work assigned. Basic principles of mathematics. Electrical theory and practices. Properties and principles of electricity and the National Electrical Code. Methods, materials and techniques used in the construction and maintenance of electrical and electronic systems. Operational characteristics of mechanical and hydraulic equipment and tools used in the installation, maintenance and repair of electronic systems. Electronic systems repair and preventative maintenance techniques and procedures. Independently perform the most difficult skilled maintenance and repair work related to electronic systems and components, and the electrical field. Ability to: Learn properties and principles of electricity and the National Electrical Code. Learn methods, materials and techniques used in the construction and maintenance of electrical and electronic systems. Learn operational characteristics of mechanical and hydraulic equipment and tools used in the installation, maintenance and repair of electronic systems. Learn electronic systems repair and preventative maintenance techniques and procedures. Operate a variety of vehicular and stationary equipment in a safe and effective manner. Use and operate hand tools, mechanical equipment and power tools and equipment in a safe and efficient manner. Read and interpret electronic schematics, diagrams, drawings and plans. Understand and follow oral and written instructions and sketches. Communicate effectively, both orally and in writing. Establish and maintain cooperative working relationships with those contacted in the course of work. Maintain effective audio/visual discrimination and perception to the degree necessary for the successful performance of assigned duties. Maintain mental capacity which allows the capability of making sound decisions and demonstrating intellectual capabilities. Troubleshoot and solve electronic system defects. Interpret, explain and enforce Division policies and procedures. Work independently in the absence of supervision. Minimum Qualifications: Electrical Instrumentation Technician I Experience: Two years of experience maintaining, repairing, and installing electrical equipment. Education/Training: High School Diploma or equivalent, supplemented by college level course work or trade school training in electrical technology or a related field. License or Certificate: Possession of, or the ability to obtain, a valid Grade I Electrical/Instrumentation Technologist Certificate from the California Water Environment Association (CWEA) within 12 months of employment Possession of a valid Class C California driver's license Electrical Instrumentation Technician II Experience: Three years of increasingly responsible experience maintaining, repairing, and installing electrical equipment at a level comparable to an Electrical Technician I. Education/Training: High School Diploma or equivalent, supplemented by college level course work or trade school training in electrical technology or a related field. License or Certificate: Possession of, or ability to obtain, a valid Grade II Electrical/Instrumentation Technologist Certificate from CWEA within 12 months of employment. Possession of a valid Class C California driver's license. Supplemental Information WORKING CONDITIONS Environmental Conditions: Inside and outside environment; travel from site to site; exposure to noise, dust, grease, smoke, fumes, gases, electrical energy, toxic materials, and inclement weather conditions. Physical Conditions: Primary functions require sufficient physical ability to walk, stand, stoop, bend, crawl, climb, and kneel; to perform heavy, moderate, or light lifting, pulling and carrying; and to operate assigned equipment and vehicles. The City of San Clemente provides excellent benefits which include:FLEXIBLE WORK SCHEDULE – Most positions work a 9/80 work schedule.HOLIDAYS – The City presently recognizes 12 regular holidays, plus two floating holidays.VACATION – Employees accumulate vacation at the rate of 104 hours per year increasing to a maximum of 176 hours based on years of service.SICK LEAVE - Accrual of 8 hours per month.INSURANCE – The City provides a comprehensive benefit package including employee medical, dental, vision.LIFE INSURANCE – Value equal to two times annual earnings up to a maximum of $100,000.DEFERRED COMPENSATION – Employees may elect to enroll in a voluntary plan and defer up to the IRS permitted annual maximum. Employees may defer up to a maximum of $24,500 annually in 2026. Individuals aged 50 and older can contribute up to $8,000 in catch-up contributions to these plans. FLEXIBLE SPENDING ACCOUNT – Employees may participate in either or both of the Health Care or Dependent Care programs.EMPLOYEE ASSISTANCE PROGRAM – The City offers full-time employees and their dependents an EAP program which provides a variety of professional services.ON-SITE FITNESS CENTER - The City provides a no fee on-site fitness center with state of the art equipment located in City Hall.RETIREMENT – The City of San Clemente is a member of the California Public Employees' Retirement System (CalPERS), and is subject to the Public Employees' Pension Reform Act (PEPRA). The retirement formula for new employees is based on the category below that the new employee falls under. Employee contribution rates will be determined by the employee's classification and requirements under PEPRA.NOTE: The City is also a member of the Social Security system. As such, Full Time employees make contributions to Social Security in addition to their CalPERS contributions. Classic Member: Retirement Formula: 2% @ 55Definition:CalPERS refers to all members that do not fit within the PEPRA definition of a "new member" as "classic members" who are subject to the Public Employees' Retirement Law (PERL). PEPRA allows a member after January 1, 2013, to retain his/her classic member retirement benefit status if the member continues his/her membership in all previous California Public Retirement System(s) by leaving his/her service credit and contributions (if any) on deposit, and the member enters into employment that results in CalPERS membership within six months of separating from the most recent California Public Retirement System. Classic member status also requires the membership date to be on or before December 31, 2012, in a California Public Retirement System in which reciprocity is established. New Member:Retirement Formula: 2% @ 62 Definition: A new member is defined in PEPRA as any of the following: A new hire who is brought into CalPERS membership for the first time on or after January 1, 2013, who has no prior membership in any California Public Retirement System.A new hire who is brought into CalPERS membership for the first time on or after January 1, 2013, who has a break in service of greater than six months with another California Public Retirement System that is subject to Reciprocity.A member who first established CalPERS membership prior to January 1, 2013, who is rehired by a different CalPERS employer after a break in service of greater than six months.

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